Showing posts with label HCQ. Show all posts
Showing posts with label HCQ. Show all posts

Friday, June 5, 2020

Lancet retracts study that linked HCQ to increased death risk

Lancet retracts study that linked HCQ to increased death risk

New Delhi: The authors of the research linking the malaria drug hydroxychloroquine and increased death risk during COVID-19 treatment have retracted The Lancet study they published as they were unable to share the full data set for an independent peer review.
“Several concerns were raised with respect to the veracity of the data and analyses conducted by Surgisphere Corporation and its founder and our co-author, Sapan Desai, in our publication,” the authors of the study wrote in the retraction statement published in The Lancet journal.
When an independent third-party peer review of Surgisphere was initiated with the consent of the co-authors of the study to evaluate the origination of the data set, and to replicate the analyses presented in the paper, the peer reviewers noted that Surgisphere would not transfer the full data set.
They were also unable to obtain details on client contracts to their servers for analysis since such transfer would violate client agreements with the company and confidentiality requirements.
“Based on this development, we can no longer vouch for the veracity of the primary data sources. Due to this unfortunate development, the authors request that the paper be retracted,” the retraction statement noted.
French officials had cited The Lancet study when they imposed a ban on the use of hydroxychloroquine in COVID-19 treatment.
Indian scientists had also cast doubts about the methodology of The Lancet study and opposed the WHO’s move to suspend trials of hydroxychloroquine.

Thursday, June 4, 2020

WHO approves trial of HCQ for potential COVID-19 treatment

WHO approves trial of HCQ for potential COVID-19 treatment

London: After suspending the hydroxychloroquine arm of a clinical trial of experimental COVID-19 drugs, the director-general of the World Health Organisation said experts had reviewed the safety data and were now recommending the trial continue as planned.
The recommendation means doctors will soon be able to resume giving the drug to patients enrolled in the UN health agency’s study.
Director-General Tedros Adhanom Ghebreyesus said Wednesday that the WHO’s safety monitoring committee for the global trial had now examined all available mortality data about hydroxychloroquine.
Some studies had suggested that people who were taking the drug for COVID-19 had a higher chance of dying than those who were not.
Tedros said: “The members of the committee recommended that there are no reasons to modify the trial protocol.”
US President Trump has said he is taking hydroxychloroquine even though he has not tested positive for the coronavirus; there are no studies that have proven the drug is effective against COVID-19.

Tedros said the executive group running the WHO’s trial endorsed the continuation of all arms of the trial, including hydroxychloroquine. Other treatments being tested, including remdesivir and an HIV combination therapy drug, were unaffected.
Tedros said that to date, more than 3,500 people have been recruited into the trial in 35 countries.